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excess glucose and glutathione The Roles of Oxidative Stress in Diabetes and COVID-19 Category_GI Support
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Its actions, however, are highly context-dependent, and under conditions of NAD + depletion, specific cell types, dosing imbalances, or advanced disease, SIRT1 may exacerbate oxidative damage by impairing repair enzyme activity, exacerbating mitochondrial dysfunction, and weakening antioxidant responses
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its dysregulation may be implicated in the pathophysiology of cancer (365)
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