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Genetic and transcriptional study of glutathione metabolism in Oenococcus oeni - ScienceDirect

However, not only does p62 prevent NRF2 binding to KEAP1, it induces autophagic degradation of KEAP1, resulting in a positive feedback loop of NRF2 activation [82]

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We recently showed that a proportion of the cellular content of GSTP is found in the ER compartment, substantiating the concept that S-glutathionylation may be a crucial regulatory process in the ER [22]