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ishigaki l-glutathione in watsons Regulation of protein O-GlcNAcylation by circadian, metabolic, and cellular signals Brain Health
Frontiers | Altered metabolic profiles of dermatomyositis with different myositis-specific autoantibodies associated with clinical phenotype
The reaction of superoxide with non-radicals is spin-forbidden
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Interestingly, based on study evidence, sex differences also critically modulate oxidative stress responses and neurodegeneration susceptibility through distinct molecular mechanisms: Females exhibit superior antioxidant capacity via estrogen‐mediated Nrf2 activation, enhancing GSH synthesis and ROS clearance, while males demonstrate heightened vulnerability to oxidative DNA/lipid damage (e.g., elevated 8‐oxoG) due to androgen‐driven mitochondrial ROS overproduction [155]
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