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While a low dose (30 mg/day) improves synaptic function, a higher dose (250 mg/day) induces copper-deficiency encephalopathy, increasing the risks associated with excessive chelation (9,242)
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Drug-induced vasculitis is usually limited to cutaneous vasculitis and arthralgia but, rarely, it can present as severe multiorgan involvement that can mimic primary systemic vasculitis
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