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In a study using Flinders Sensitive Line (FSL) versus Flinders Resistant Line (FRL) rats, the intracerebral application of NPS resulted in reduced depression and anxiety-related behaviors in FSL animals, suggesting its anxiolytic and antidepressant role [161]
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To improve outcome reporting and athlete safety, we recommend that during history-taking, clinicians explicitly inquire about “dietary or sports supplements” and provide counseling and heightened suspicion regarding potential contaminants
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