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Xanthohumol, a sesquiterpene from hop ( Humulus lupulus ) also shows chemopreventive activity, inducing antioxidant and phase II detoxification enzymes [210]
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In hepatocellular carcinoma xenografts, MVD inhibitors and atorvastatin reduced tumor growth, increased lipid peroxidation markers and sensitized tumors to GPX4 inhibitor co‑treatment
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