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Therefore, it appears that with food allergy, stopping oral therapy would result in a loss of desensitization, although it is not known if the same is true for oral tolerance to ADAs

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The importance of phosphorylation in DOR desensitization was challenged by the work of Qiu and colleagues who studies those processes using a DOR mutant in which all Ser/Thr residues in the C-terminus region were mutated to Ala (Qiu et al., 2007)