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causes of low glutathione levels Glutathione's role in immune function and energy glutathione deficiency symptoms
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In vitro studies have shown that AA enhances the production of ROS and reactive nitrogen species (RNS), decreases the activity of related metabolic and binding enzymes, disrupts the antioxidant defense system, inhibits the cellular total antioxidant capacity, alters cell morphology, and causes irreversible damage to cells
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Endothelial dysfunction—marked by reduced nitric oxide (NO) bioavailability, impaired vasodilation, and increased vascular permeability—is a primary feature in both microvascular and macrovascular diabetic complications [25]
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