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The reason I say that is that even if you aren't considering taking peptides or already taking peptides, peptides and some of these other compounds I've mentioned sit somewhere between doing nothing except diet and exercise, supplements, which I see as the next step up the ladder in terms of augmenting your health approaches, and then of course, there are a number of prescription drugs, including hormone therapies, such as growth hormone therapies, testosterone therapies, and a number of other things that yes, can modify those hormone pathways, they are, in fact, hormones, but they actually can shut down one's natural production of those hormone pathways
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Recently report address that GH inhibits DNA damage repair by suppressing ATM and DNA-PKcs activities in colon cells, leading to decreased DNA repair by both HR and NHEJ ( In vivo , injecting hGH to human subjects for 6 weeks results in increased lymphocyte DNA damage, and the damage can last for a long time after hGH withdrawal ( IGF1 Promotes DNA Damage Repair of DNA DBSs IGF1 and IGF1R are necessary for nucleotide excision repair (Loesch et al., 2016)
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