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Interestingly, organosulfur compounds bearing NAC-like structures have been identified in Allium species, with Allium cepa (red onion) containing approximately 45 mg/kg (Dorrigiva et al., 2021)

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however, no differences were observed in T3, T4, or TSH levels.31 An increased risk of osteopenia—up to fourfold higher—has been reported in patients with PG vs individuals without gray hair.32 Nevertheless, more recent studies failed to confirm this association.33 In cases of PG, a laboratory work-up may be necessary, including iron studies, vitamin B12, folic acid, 25-hydroxyvitamin D, thyroid profile, and antithyroid antibodies.31–33 Clinical features Gray hair primarily results from an optical phenomenon