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These enzymes were tolerant of the unnatural 3-methyl-2-benzothiophenic acid, which was fed to a ΔnosL Streptomyces actuosus mutant and was incorporated to generate 442b , the thiophene analog of 442a
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In a 2018 study published in Current Pharmaceutical Design , researchers compared the effectiveness of BPC-157 to that of various standard peptidergic angiogenic growth factors (EGF, FGF, and VEGF) and numerous carriers for treating gastrointestinal ulcer healing and tendon, ligament, muscle, and bone healing
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