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So that nerves at the back of the eye, and probably every cell type we looked at, perhaps with the exception of eggs and sperms, and certain stem cells, they lose their identity, they don’t have what we call a youthful gene expression pattern anymore

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Similarly, treating the DRG neurons with paclitaxel significantly hampered microtubule dynamics, promoted the formation of retraction bulb-like structures at the distal growing tips (Gornstein and Schwarz, 2017), and thus markedly impaired the neurite outgrowth of cultured DRG neurons (Chine et al., 2019a)